ive changed salts several times and never saw a problem, i think if its done slow and small amount replaced there shouldnt be an issue, mind you all the salts i changed from and to were similar in parameters so there wasnt much of a difference.
hey steve the new IO is vertually identical to existing Reef Crystals now, in fact you may have been better off sticking with IO, some of the posts from the big guns and chemists i see suggest its at optimum reef levels now, apparently its going to be a decent salt where not much dosing is required, unlike the old IO, which had poor levels